ISOLATED COMPLEX LIMB REDUCTION ABNORMALITY DIAGNOSED ANTENATALLY

Congenital limb reduction defects are rare lesions that are usually as sociated with other anomalies. Terminal defects are the commonest redu ction defects. The aetiology seems to be multifactorial. We present a case of congenital terminal deficiency of the same side of the upper a nd lower limbs diagnosed by ultrasound scanning during the second trim ester. The fetus had an absent right fibula and right foot, a hypoplas tic right hand and left talipes equinovarus. The pregnancy was termina ted. Micrognathia was the only associated anomaly found on postmortem examination. The cause of this isolated anomaly is unknown but, becaus e of the very variable presentation of limb reduction defects, could p ossibly fit into the categories so far described in the literature.