Objective: To determine the prevalence and impact of multiple chronic
conditions on children's health status and utilization of health servi
ces. Design: Analysis of the 1988 National Health Interview Survey on
Child Health.Setting: Nationally representative sample of the U.S. civ
ilian, noninstitutionalized population. Participants: A total of 17,71
0 children less than 18 years of age selected in a stratified cluster
sampling of U.S. households. Intervention: None. Results: We estimated
that fewer than 5% of children have multiple (two or more) chronic co
nditions and that less than 1% of children had three or more such cond
itions. However, despite this low overall prevalence, some notable fea
tures of multiple chronic conditions stand out. Many of the most preva
lent condition-pairs were allergy related, and the rates of co-occurre
nce of these disorders were generally higher than would be predicted o
n the basis of prevalence rates for the individual conditions. Childre
n with multiple chronic conditions had more mental and physical health
problems and used substantially more health services than other child
ren. For example, the prevalence of developmental delay, learning disa
bilities, and emotional and behavioral problems increased sharply with
the number of chronic conditions reported. Notable deterioration in s
uch health status measures as days in bed, school absences, and activi
ty limitation was also observed with increasing numbers of chronic con
ditions. Similarly, utilization of hospital and physician services inc
reased in tandem with increasing numbers of chronic conditions. Conclu
sions: Children who have multiple conditions of a chronic nature, even
if few in number, have increased morbidity across a variety of measur
es.