A case of a large polypoidal gallbladder carcinoma presenting with emp
yema is described, Heterogeneous echoes filled the gallbladder lumen o
n gray-scale sonography. Color Doppler ultrasound detected vascularity
within the gallbladder lumen, thereby differentiating the intralumina
l tumor from isoechoic sludge and pus. Correlative computed tomography
showed an enhancing intraluminal mass, with small enhancing vessels t
hat corresponded to those seen with color Doppler sonography.