SOLITARY BONE PLASMACYTOMA TERMINALLY DEVELOPED MYELOMA WITH MULTIPLEEXTRAMEDULLARY LESIONS AND MYELOMATOUS PLEURAL EFFUSION AND ASCITES

A rare case of IgG-kappa type multiple myeloma associated with multipl e extramedullary tumor-forming lesions and myelomatous pleural effusio n and ascites is reported. The patient suffered from sternal solitary plasmacytoma, which 5 years later developed disseminated tumor formati on with myeloma cells mostly in the soft tissues. At autopsy, multiple extramedullary lesions particularly in the abdominal cavity and myelo matous pleural effusion and ascites were observed without diffuse infi ltration of myeloma cells in the bone marrow. The disseminating change from solitary bone plasmacytoma to extramedullary tumor formation see n in this case seemed to be unusual but suggestive of a feature of an aggressive tendency of multiple myeloma.