Ke. Wiemer et al., THE COMBINATION OF COCULTURE AND SELECTIVE ASSISTED HATCHING - RESULTS FROM THEIR CLINICAL-APPLICATION, Fertility and sterility, 61(1), 1994, pp. 105-110
Objective: To establish pregnancies using a combination of coculture a
nd selective assisted hatching. Design: Clinical application for a sel
ected group of patients. Not a controlled study. Setting: Private infe
rtility practice. Patients: Women with high basal FSH levels, ovulator
y disorders, and multiple failed IVF attempts. Main Outcome Measures:
Pregnancy and implantation rates. Results: Of the 95 patients who had
coculture and selective assisted hatching, 45 (47.0%) have an ongoing
pregnancy with a 23.0% implantation rate. Conclusion: The combination
of coculture and assisted hatching produced acceptable pregnancy and i
mplantation rates within the selected patient population.