MALIGNANT LYMPHOID-CELL SUBPOPULATIONS DETECTED BY LECTIN-BINDING

Peripheral blood lymphocytes and bone marrow cells from the patients w ith acute lymphoblastic leukemia, chronic lymphocytic leukemia, hairy cell leukemia and non-Hodgkin's lymphomas were assessed for staining w ith the panel of lectins (PNA, HPL, LCL, RCA-1, SBA, SJA). These cell populations have also been characterized enzymocytochemically and for surface antigens with a series of monoclonal antibodies. We found that the application of the lectin-peroxidase techniques may be a helpful tool for classification and diagnosis of human lymphoproliferative dis eases.