THE ETIOLOGY AND PATHOGENESIS OF LARYNGEAL CARCINOMA

Authors
KOUFMAN JA BURKE AJ
Citation
Ja. Koufman et Aj. Burke, THE ETIOLOGY AND PATHOGENESIS OF LARYNGEAL CARCINOMA, Otolaryngologic clinics of North America, 30(1), 1997, pp. 1
Citations number
121
Categorie Soggetti
Otorhinolaryngology
Journal title
Otolaryngologic clinics of North America → ACNP
ISSN journal
00306665
Volume
30
Issue
1
Year of publication
1997
Database
ISI
SICI code
0030-6665(1997)30:1<1:TEAPOL>2.0.ZU;2-#
Abstract
Epidemiologic data suggest that the etiology and pathogenesis of laryn geal carcinoma are influenced by environmental and lifestyle-related f actors, such as tobacco use, ethanol consumption, and exposure to toxi c substances. In addition, dietary factors, irradiation, papilloma vir us infection, and laryngopharyngeal reflux seem to be significant carc inogenic cofactors. This article presents a multifactorial model of la ryngeal mucosal carcinogenesis.