Jp. Barker et al., RETROBULBAR BLOCK FAILS TO PREVENT AN INCREASE IN SERUM CORTISOL CONCENTRATION ON EMERGENCE FROM ANESTHESIA AFTER CATARACT-SURGERY, British Journal of Anaesthesia, 72(1), 1994, pp. 119-121
We have studied 30 elderly patients undergoing cataract surgery, alloc
ated randomly to receive general anaesthesia, local anaesthesia by ret
robulbar block or general anaesthesia combined with retrobulbar block
given after induction. Retrobulbar block alone prevented the increases
in circulating cortisol and glucose values which occurred in those pa
tients receiving general anaesthesia alone. Retrobulbar block given af
ter induction of general anaesthesia, however, suppressed the cortisol
and glucose responses during surgery, but did not prevent a marked in
crease in cortisol concentrations during the immediate postoperative p
eriod. The results suggest a hormonal response to emergence from anaes
thesia which has hitherto been masked by the stress response to surger
y itself.