THE COSTELLO SYNDROME - REPORT OF A CASE AND REVIEW OF THE LITERATURE

A 5-year-old girl with the Costello syndrome is reported. Her clinical manifestations included growth and developmental delay, a distinct fa cial appearance with sparse and curly hair, nasal papillomata, and dar k loose skin of the hands and feet. These manifestations, especially n asal papilloma, an age-dependent anomaly, are distinct in the Costello syndrome.