PROGRESSION OF REFRACTORY-ANEMIA WITH RINGED SIDEROBLASTS (RARS) TO B-ACUTE LYMPHOBLASTIC-LEUKEMIA

Authors
SUVAJDZIC ND JANKOVIC GM BOGDANOVIC AD COLOVIC MD ROLOVIC Z
Citation
Nd. Suvajdzic et al., PROGRESSION OF REFRACTORY-ANEMIA WITH RINGED SIDEROBLASTS (RARS) TO B-ACUTE LYMPHOBLASTIC-LEUKEMIA, Haematologia, 25(4), 1993, pp. 283-285
Citations number
NO
Categorie Soggetti
Hematology
Journal title
Haematologia → ACNP
ISSN journal
00176559
Volume
25
Issue
4
Year of publication
1993
Pages
283 - 285
Database
ISI
SICI code
0017-6559(1993)25:4<283:PORWRS>2.0.ZU;2-J
Abstract
The study describes progression of refractory anaemia with ring sidero blasts (RARS) of 3 years' duration to B-acute lymphoblastic leukaemia (ALL). Development of ALL in this patient was preceded by the deterior ation of dyserythropoiesis, leukopenia and an increase of blasts in th e bone marrow. Our case may represent an additional evidence to the hy pothesis that a primary pathogenetic lesion in myelodysplastic syndrom e occurs at the level of the pluripotent stem cell.