BETA-LACTAMS FROM ESTER ENOLATES AND N-(TRIMETHYLSILYL)IMINES - A SIMPLE ROUTE TO 1-BETA-METHYL PS-5

Authors
BANDINI E CAINELLI G MARTELLI G PANUNZIO M SPUNTA G
Citation
E. Bandini et al., BETA-LACTAMS FROM ESTER ENOLATES AND N-(TRIMETHYLSILYL)IMINES - A SIMPLE ROUTE TO 1-BETA-METHYL PS-5, Gazzetta chimica italiana, 123(9), 1993, pp. 509-513
Citations number
48
Categorie Soggetti
Chemistry
Journal title
Gazzetta chimica italiana → ACNP
ISSN journal
00165603
Volume
123
Issue
9
Year of publication
1993
Pages
509 - 513
Database
ISI
SICI code
0016-5603(1993)123:9<509:BFEEAN>2.0.ZU;2-J
Abstract
The synthesis of a novel carbapenem antibiotic, 1beta-methyl PS-5, is described. The key step. involved the ester enolate-metalloimine cyclo addition.