Hyperbaric oxygen therapy provided in specially designed pressure cham
bers is currently the treatment of choice for decompression sickness,
arterial gas embolism, and serious carbon monoxide poisoning. It is an
important adjunct in the treatment of gas gangrene, chronic osteomyel
itis, radiation injury, and indolent wounds. The potential benefit in
the treatment of thermal burns is not well appreciated. Hyperbaric oxy
gen therapy may significantly reduce morbidity, mortality, and cost of
care. The application of this technology based on the demonstrated be
neficial effects on the pathophysiology of the burn wound merits consi
deration in selected patients.