PUVA TREATMENT AND CHOROIDAL MALIGNANT-MELANOMA

Citation
G. Haciyakupoglu et al., PUVA TREATMENT AND CHOROIDAL MALIGNANT-MELANOMA, Acta ophthalmologica, 71(6), 1993, pp. 846-849
Citations number
21
Categorie Soggetti
Ophthalmology
Journal title
ISSN journal
0001639X
Volume
71
Issue
6
Year of publication
1993
Pages
846 - 849
Database
ISI
SICI code
0001-639X(1993)71:6<846:PTACM>2.0.ZU;2-G
Abstract
Choroidal malign melanoma showing rapid progression in a boy 17 years old is presented. The patient was under therapy with methoxy psoralen + Ultraviolet A (PUVA) for psoriasis vulgaris. He had undergone compl ete ophthalmologic examinations with three-month intervals from the be ginning of this therapy. The tumor was detected in the seventh month, rapidly enlarging within the next twenty days, and eventually leading to enucleation. PUVA is known to be a risk factor for cutaneous malign melanoma. However, there is no reported incidence of choroidal malign melanoma in PUVA treated patients. To our knowledge, this is the only case showing the possible role of PUVA therapy as a predisposing fact or in the development of uveal malign melanoma.