ELECTROREDUCTION OF 5-CHLORO-7-NITROBENZOFURAN DERIVATIVE - A FACILE ACCESS TO A KEY INTERMEDIATE FOR ACAT INHIBITORS

Authors
TORII S OKUMOTO H MINOSHIMA T KUROZUMI S
Citation
S. Torii et al., ELECTROREDUCTION OF 5-CHLORO-7-NITROBENZOFURAN DERIVATIVE - A FACILE ACCESS TO A KEY INTERMEDIATE FOR ACAT INHIBITORS, Synlett, (1), 1994, pp. 68-68
Citations number
4
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synlett → ACNP
ISSN journal
09365214
Issue
1
Year of publication
1994
Pages
68 - 68
Database
ISI
SICI code
0936-5214(1994):1<68:EO5D-A>2.0.ZU;2-6
Abstract
Electroreduction of nitro-2,2,4,6-tetramethyl-2,3-dihydrobenzo[b]furan in a DMF-(t)BuOH/Bu(4)NBF(4)/Zn-Zn system effected conversion of the nitro group into amine and ensuing removal of the chlorine atom in one pot, leading to a pivotal precursor for ACAT inhibitors.