Neutral atom and pick-up ion flux computations using a hot model for h
ydrogen, helium, oxygen and neon along the trajectory of the Ulysses s
pacecraft, including predictions for the Extended Mission are reported
and discussed. The feasibility of using absolute pick-up ion fluxes a
nd pick-up ion flux ratios to derive the orientation of the heliospher
ic upwind-downwind axis is investigated. Finally, the ratio of pick-up
ion and neutral fluxes for helium and oxygen expected to be seen by t
he Ulysses spacecraft are presented and their relevance for a determin
ation of the long- and short-term averages of the total ionization fre
quencies of neutrals is discussed.