Ms. Singh Ov",sangeeta,"khanna et al., SYNTHESIS OF 2,3-DISUBSTITUTED-6-[1-ACYL-5-ARYL (OR HETARYL)-4,5-DIHYDROPYRAZOL-3-YL]CHROMONES OF POTENTIAL MEDICINAL INTEREST, Indian journal of chemistry. Sect. B: organic chemistry, including medical chemistry, 32(12), 1993, pp. 1241-1248
The tide compounds (12-19) have been synthesized by the condensation o
f 2,3-disubstituted-6-[(3-aryl or hetaryl)acryloyl]chromones (8-11) wi
th hydrazine hydrate in the presence of formic or acetic acid. Their s
tructures have been elucidated on the basis of elemental analyses and
spectral data. Some of the compounds have also been screened for their
anticomplementary, CNS and antiinflammatory activities.