Pp. Singh et B. Rai, TOPOLOGICAL INVESTIGATIONS OF THE BIOLOGICAL-ACTIVITY OF DRUGS, Indian journal of chemistry. Sect. B: organic chemistry, including medical chemistry, 32(12), 1993, pp. 1258-1264
A simple approach has been employed to show that while the biological
effects of structurally non-specific drug is controlled by its connect
ivity index of the first order, 1xi, that of structurally specific dru
g is governed not only by its chemical specificity but also by its 1xi
.