TOPOLOGICAL INVESTIGATIONS OF THE BIOLOGICAL-ACTIVITY OF DRUGS

Authors
SINGH PP RAI B
Citation
Pp. Singh et B. Rai, TOPOLOGICAL INVESTIGATIONS OF THE BIOLOGICAL-ACTIVITY OF DRUGS, Indian journal of chemistry. Sect. B: organic chemistry, including medical chemistry, 32(12), 1993, pp. 1258-1264
Citations number
45
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Indian journal of chemistry. Sect. B: organic chemistry, including medical chemistry → ACNP
ISSN journal
03764699
Volume
32
Issue
12
Year of publication
1993
Pages
1258 - 1264
Database
ISI
SICI code
0376-4699(1993)32:12<1258:TIOTBO>2.0.ZU;2-D
Abstract
A simple approach has been employed to show that while the biological effects of structurally non-specific drug is controlled by its connect ivity index of the first order, 1xi, that of structurally specific dru g is governed not only by its chemical specificity but also by its 1xi .