USE OF CELL-CULTURES IN TOPICAL TREATMENT OF BURN WOUNDS

The article deals with the results of using cultivated allofibroblasts in topical treatment of burn wounds. Allofibroblasts obtained from th e derma of burnt individuals were transplanted to the burn wounds of 2 8 patients. In 12 among 15 patients (80 %) with IIIa-IIIb degree burns transplantation induced epithelialization of the burns in 12.1 +/- 2, 4 days. Thirteen patients had deep burns, only in 3 of them with a cir cumscribed burn area transplantation proved effective. Complications o f transplantation were encountered in 5 patients - rejection of the tr ansplant in 2 and its suppuration in 3 patients. Allofibroblast transp lantation may be applied as an independent method of treatment in IIIa , b degree burns.