Aj. Kirsch et al., PRELIMINARY-RESULTS OF LASER-TISSUE WELDING IN EXTRAVESICAL REIMPLANTATION OF THE URETERS, The Journal of urology, 151(2), 1994, pp. 514-517
One exciting potential use of laparoscopic technology is the extravesi
cal reimplantation of the ureters. We have assessed the efficacy of la
ser-activated fibrinogen solder to close vesical muscle flaps over sub
mucosal ureters (Lich-Gregoir technique) in a canine model. Four dogs
were subjected to unilateral flap closures via a protein solder (indoc
yanine green and fibrinogen) applied to the bladder serosa and exposed
to 808 nm. continuous wave diode laser energy. Contralateral reimplan
tation was performed using 4-zero vicryl muscle flap closures (control
s). At 7, 14 and 28 days postoperatively, intravenous pyelograms confi
rmed bilateral ureteral patency. At intravesical pressures above 100 c
m. H2O, there was no evidence of wound disruption in either group. Non
disrupted wound closures were sectioned and strained until ultimate br
eakage to determine tensile strength. At each study interval the laser
-welded closures withstood greater stress than the controls. Although
these data represent single tissue samples and are not amenable to sta
tistical analysis, laser-welded closures appeared to be stronger at ea
ch study interval. In conclusion, laser-welded vesical wound closures
appear at least as strong as suture closures in the canine model.