A SHORT SYNTHESIS OF THE ANTIMITOTIC ALLYLIC DIEPOXIDE FUNCTIONAL ARRAY OF SPATOL

Authors
MURTHI KK SALOMON RG
Citation
Kk. Murthi et Rg. Salomon, A SHORT SYNTHESIS OF THE ANTIMITOTIC ALLYLIC DIEPOXIDE FUNCTIONAL ARRAY OF SPATOL, Tetrahedron letters, 35(4), 1994, pp. 517-520
Citations number
13
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
35
Issue
4
Year of publication
1994
Pages
517 - 520
Database
ISI
SICI code
0040-4039(1994)35:4<517:ASSOTA>2.0.ZU;2-T
Abstract
An alpha-lithio epoxide intermediate provides a highly stereocontrolle d synthesis of the spatol allylic diepoxide, a functional array that i s uniquely effective at inhibiting mitosis.