O-TRIMETHYLSILYLPHENYLLITHIUM AS A SYNTHETIC EQUIVALENT OF O-HALOPHENYLLITHIUM

Authors
TAKAHASHI M HATANO K KIMURA M WATANABE T ORIYAMA T KOGA G
Citation
M. Takahashi et al., O-TRIMETHYLSILYLPHENYLLITHIUM AS A SYNTHETIC EQUIVALENT OF O-HALOPHENYLLITHIUM, Tetrahedron letters, 35(4), 1994, pp. 579-582
Citations number
7
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
35
Issue
4
Year of publication
1994
Pages
579 - 582
Database
ISI
SICI code
0040-4039(1994)35:4<579:OAASEO>2.0.ZU;2-S
Abstract
The reaction of o-trimethylsilylphenyllithium with carbonyl compounds and subsequent halogenodesilylation with ICI afforded o-iodophenylcarb inols in good yields, showing the usefulness of o-trimethylsilylphenhy llithium as a synthetic equivalent of o-iodophenyl anion. The reaction via a protected o-trimethylsilylphenylcarbinol is also shown.