REGIONAL MAPPING OF THE HUMAN NSP GENE TO CHROMOSOME REGION 14Q21-]Q22 BY FLUORESCENCE IN-SITU HYBRIDIZATION ANALYSIS

Authors
KOOLS PFJ ROEBROEK AJM VANDEVELDE HJK MARYNEN P BULLERDIEK J VANDEVEN WJM
Citation
Pfj. Kools et al., REGIONAL MAPPING OF THE HUMAN NSP GENE TO CHROMOSOME REGION 14Q21-]Q22 BY FLUORESCENCE IN-SITU HYBRIDIZATION ANALYSIS, Cytogenetics and cell genetics, 66(1), 1994, pp. 48-50
Citations number
5
Categorie Soggetti
Cytology & Histology","Genetics & Heredity
Journal title
Cytogenetics and cell genetics → ACNP
ISSN journal
03010171
Volume
66
Issue
1
Year of publication
1994
Pages
48 - 50
Database
ISI
SICI code
0301-0171(1994)66:1<48:RMOTHN>2.0.ZU;2-#
Abstract
Genetic sequences of the novel NSP gene, which encodes neuroendocrine- specific proteins, were isolated from cDNA libraries constructed with mRNA isolated from human lung carcinoma cells. Hybridization analysis of a panel of human x mouse cell hybrids with an 0.8-kb NSP cDNA probe indicated that the human NSP gene is probably located on chromosome 1 4. Fluorescence in situ hybridization analysis of metaphase chromosome s using overlapping genomic clones of NSP as a probe localized the NSP gene to chromosome region 14q21 --> q22.