A concentric airlift reactor and stirred tank reactors have been compa
red for use with immobilized enzyme. Mixing efficiency, specific power
input, shear stress, and enzyme stability were compared and discussed
. Immobilized penicillin acylase was used as an example for this study
. The airlift reactor was found to be superior to the stirred tank rea
ctors in enzyme stability and specific power requirement. Because of l
ower shear stress and less broken fine enzyme fragments, using an airl
ift reactor may also be advantageous for downstream product separation
.