ONDANSETRON IN THE CONTROL OF CHEMOTHERAPY-INDUCED AND RADIOTHERAPY-INDUCED EMESIS IN CHILDREN WITH MALIGNANCIES

Authors
ZOUBEK A KRONBERGER M PUSCHMANN A GADNER H
Citation
A. Zoubek et al., ONDANSETRON IN THE CONTROL OF CHEMOTHERAPY-INDUCED AND RADIOTHERAPY-INDUCED EMESIS IN CHILDREN WITH MALIGNANCIES, Anti-cancer drugs, 4, 1993, pp. 17-21
Citations number
18
Categorie Soggetti
Oncology,"Pharmacology & Pharmacy
Journal title
Anti-cancer drugs → ACNP
ISSN journal
09594973
Volume
4
Year of publication
1993
Supplement
2
Pages
17 - 21
Database
ISI
SICI code
0959-4973(1993)4:<17:OITCOC>2.0.ZU;2-M
Abstract
The management of chemotherapy-induced nausea and emesis presents a ma jor problem in children with cancer. The anti-emetic properties of the 5-HT3 receptor antagonist ondansetron are well documented in adults r eceiving cytotoxic chemotherapy. Experience in the treatment of childr en is still limited. Here we present a review of the literature on the anti-emetic treatment with ondansetron in children. Moreover, we prov ide recommendations on the use of ondansetron during anti-neoplastic c hemotherapy and radiotherapy in pediatric oncology.