Pure anti-Do(a) stimulated by pregnancy was detected in 2 non-transfus
ed females during routine antenatal screening. Anti-Do(a) occurs rarel
y and has generally been reported in combination with other antibodies
. The first, and only report to date, of pure anti-Do(a) was also stim
ulated by pregancy. We believe these instances to be only the second a
nd third reported cases of pure anti-Do(a).