We consider the properties of vortices in superfluid helium-4 at negat
ive pressure. Based on a simple density-functional model, we first cal
culate the density profile in the vicinity of a vortex. We then determ
ine the negative pressure at which the vortex becomes unstable against
a uniform radial expansion all along its length. This instability occ
urs at -6.9 bars. We then calculate the pressure-dependence of the ene
rgy DELTAE(nuc) required to nucleate a bubble on the vortex. The resul
ts of this calculation are used to estimate the effect of quantized vo
rtices on the rate at which bubbles are nucleated in superfluid helium
at negative pressure.