A CASE OF CHRONIC EPILEPTIC ENCEPHALOPATHY OF NEONATAL ONSET - A PROBABLE CONCERN OF HUMAN CYTOMEGALOVIRUS

Authors
KOHYAMA J SUZUKI N KAJIWARA M SHIMOHIRA M IWAKAWA Y
Citation
J. Kohyama et al., A CASE OF CHRONIC EPILEPTIC ENCEPHALOPATHY OF NEONATAL ONSET - A PROBABLE CONCERN OF HUMAN CYTOMEGALOVIRUS, Brain & development, 15(6), 1993, pp. 448-452
Citations number
16
Categorie Soggetti
Neurosciences
Journal title
Brain & development → ACNP
ISSN journal
03877604
Volume
15
Issue
6
Year of publication
1993
Pages
448 - 452
Database
ISI
SICI code
0387-7604(1993)15:6<448:ACOCEE>2.0.ZU;2-9
Abstract
A 10-year-old male patient, who had suffered from intractable convulsi ons from the neonatal period, is presented. Serial brain images sugges ted slow, gradual destruction of neural elements. Human cytomegaloviru s (HCMV) DNA was detected in his cerebrospinal fluid (CSF) by means of the polymerase chain reaction. Intrathecal interferon had a favorable effect on his seizures. We assume a close relationship between HCMV a nd some chronic types of epileptic encephalitis/encephalopathy.