SYNTHETIC APPROACH TO APHIDICOLAN AND STEMODAN BASIC SKELETONS USING A TANDEM PRINCIPLE [2+2+2] AND [4+2] CYCLOADDITION REACTIONS

Authors
STAMMLER R HALVORSEN K GOTTELAND JP MALACRIA M
Citation
R. Stammler et al., SYNTHETIC APPROACH TO APHIDICOLAN AND STEMODAN BASIC SKELETONS USING A TANDEM PRINCIPLE [2+2+2] AND [4+2] CYCLOADDITION REACTIONS, Tetrahedron letters, 35(3), 1994, pp. 417-420
Citations number
13
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
35
Issue
3
Year of publication
1994
Pages
417 - 420
Database
ISI
SICI code
0040-4039(1994)35:3<417:SATAAS>2.0.ZU;2-#
Abstract
A strategy based upon the ''Tandem Principle'' : coupling of the cobal t catalyzed [2 + 2 + 2] cycloaddition and an intramolecular [4 + 2] Di els-Alder reaction allowed the formation of the stemodan skeleton in 1 1 high yield steps starring from C-ethoxycarbonyl cyclohexanone.