ANOMALOUS ENANTIOSELECTIVITY IN THE SHARPLESS CATALYTIC ASYMMETRIC DIHYDROXYLATION REACTION OF 1,1-DISUBSTITUTED ALLYL ALCOHOL DERIVATIVES

Authors
HALE KJ MANAVIAZAR S PEAK SA
Citation
Kj. Hale et al., ANOMALOUS ENANTIOSELECTIVITY IN THE SHARPLESS CATALYTIC ASYMMETRIC DIHYDROXYLATION REACTION OF 1,1-DISUBSTITUTED ALLYL ALCOHOL DERIVATIVES, Tetrahedron letters, 35(3), 1994, pp. 425-428
Citations number
14
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
35
Issue
3
Year of publication
1994
Pages
425 - 428
Database
ISI
SICI code
0040-4039(1994)35:3<425:AEITSC>2.0.ZU;2-P
Abstract
The Sharpless asymmetric dihydroxylation (AD) reaction has been examin ed on a number of 1,1-disubstituted allyl alcohol derivatives. In the majority of substrates studied, the product diols had ee's in the 9-11 % range and had absolute stereochemistry opposite to that predicted us ing the Sharpless steric model.