LANTHANIDE(III) TRIFLUOROMETHANESULFONATES AS EXTRAORDINARILY EFFECTIVE NEW CATALYSTS FOR THE AMINOLYSIS OF 1,2-EPOXIDES

Authors
CHINI M CROTTI P FAVERO L MACCHIA F PINESCHI M
Citation
M. Chini et al., LANTHANIDE(III) TRIFLUOROMETHANESULFONATES AS EXTRAORDINARILY EFFECTIVE NEW CATALYSTS FOR THE AMINOLYSIS OF 1,2-EPOXIDES, Tetrahedron letters, 35(3), 1994, pp. 433-436
Citations number
6
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
35
Issue
3
Year of publication
1994
Pages
433 - 436
Database
ISI
SICI code
0040-4039(1994)35:3<433:LTAEE>2.0.ZU;2-2
Abstract
Lanthanide(lll) trifluoromethanesulfonates (triflates), such as Yb(OTf )3, Nd(OTf)3 and Gd(OTf)3, catalyze in a extraordinarily efficient way the aminolysis of 1,2-epoxides, affording the corresponding beta-amin o alcohols, at room temperature and in a non-protic solvent (CH2Cl2 or toluene), in very good yields. The reactions are completely anti ster eoselective and highly regioselective.