SYNTHESIS OF AN UNNATURAL PRODUCT - 4,4' BIARYL FORMATION AS A MACROCYCLIZATION STEP

Authors
PATEL HK KILBURN JD LANGLEY GJ EDWARDS PD MITCHELL T SOUTHGATE R
Citation
Hk. Patel et al., SYNTHESIS OF AN UNNATURAL PRODUCT - 4,4' BIARYL FORMATION AS A MACROCYCLIZATION STEP, Tetrahedron letters, 35(3), 1994, pp. 481-484
Citations number
23
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
35
Issue
3
Year of publication
1994
Pages
481 - 484
Database
ISI
SICI code
0040-4039(1994)35:3<481:SOAUP->2.0.ZU;2-A
Abstract
A novel macrocyle featuring a crown ether ring, amide functionality an d a rigid biaryl unit has been prepared as a potential receptor for sm all peptidic guests. The synthesis of the macrocyle includes a palladi um catalysed biaryl formation as the ring-closing step.