M. Kozempel et M. Kurantz, THE ISOMERIZATION KINETICS OF LACTOSE TO LACTULOSE IN THE PRESENCE OFBORATE, Journal of chemical technology and biotechnology, 59(1), 1994, pp. 25-29
The kinetics of the isomerization of lactose to lactulose in the prese
nce of boric acid and NaOH was studied. A first order equation fits th
e data for the rate controlling reaction-the formation of a boric acid
-lactulose complex. Since the reaction is optimum at a molar ratio of
boric acid to lactose of 1.0 and pH 11, a model was developed for appl
ication at these reaction conditions.