We present a simple alternative to Mackey's account of the (infinite)
inequivalent quantizations possible on a coset space G/H. Our reformul
ation is based on the reduction G-->G/H and employs a generalized form
of Dirac's approach to the quantization of constrained systems. When
applied to the four-sphere S-4 similar or equal to Spin(S)/Spin(4), th
e inequivalent quantizations induce relativistic spin and a background
BPST instanton; thus they might provide a natural account of both of
these physical entities.