DOES A SYNTHETIC PEPTIDE-CONTAINING THE LEUCINE-ZIPPER DOMAIN OF C-MYB FORM AN ALPHA-HELICAL STRUCTURE IN SOLUTION

Authors
EBNETH A ADERMANN K WOLFES H
Citation
A. Ebneth et al., DOES A SYNTHETIC PEPTIDE-CONTAINING THE LEUCINE-ZIPPER DOMAIN OF C-MYB FORM AN ALPHA-HELICAL STRUCTURE IN SOLUTION, FEBS letters, 337(3), 1994, pp. 265-268
Citations number
19
Categorie Soggetti
Biophysics,Biology
Journal title
FEBS letters → ACNP
ISSN journal
00145793
Volume
337
Issue
3
Year of publication
1994
Pages
265 - 268
Database
ISI
SICI code
0014-5793(1994)337:3<265:DASPTL>2.0.ZU;2-L
Abstract
We have examined a synthetic peptide containing the putative leucine z ipper domain of the chicken c-myb proto-oncogene using circular dichro ism (CD) spectroscopy. The peptide adopts an alpha-helical structure o nly at low temperatures and in the presence 2,2,2-trifluoroethanol.