CLINICAL-TRIAL TO ASSESS AND COMPARE OXIBENDAZOLE AND PYRANTEL PAMOATE TREATMENT IN HORSES

Two groups of 12 horses each were treated with 10 mg/kg of oxibendazol e (OXB) or 6.6 mg/kg of pyrantel pamoate (PYR) orally. A third group o f 12 horses served as an untreated control group. Fecal examinations w ere done before treatment and on post-treatment Day (PTD) 14. Strongyl e egg per gram (EPG) counts and larvae per gram (LPG) counts were perf ormed. Third stage larvae cultures demonstrated the majority of the la rvae were small strongyles. Results of fecal counts before treatment w ere similar in all three groups of horses. Following treatment, fecal egg and larvae counts on PTD 14 for the OXB treated horses had a 98.6% and 99.6% reduction in mean strongyle EPG and LPG counts, respectivel y. PYR-treated horses had a 88.5% and 96.4% reduction of strongyle EPG and LPG counts, respectively. Adverse reactions following treatment w ith OXB or PYR were not observed.