Although benign vascular tumors of the liver are extremely common (hem
angioma is the most common), malignant vascular tumors of the liver ar
e very rare. In the adult, these tumors are angiosarcoma, epithelioid
hemangioendothelioma, and Kaposi sarcoma. All hepatic malignant vascul
ar tumors share histologic characteristics, grow around and into vesse
ls, and are grossly multifocal. They may be misdiagnosed histologicall
y, particularly if only a biopsy sample is available. Although imaging
findings are often nonspecific, some features are suggestive or even
characteristic of these neoplasms. Such features include previous expo
sure to thorium dioxide (Thorotrast) in cases of angiosarcoma, coalesc
ence of multiple nodules into large peripheral masses in epithelioid h
emangioendothelioma, and association between acquired immunodeficiency
syndrome and cutaneous involvement in Kaposi sarcoma. Because hepatic
malignant vascular tumors are often multiple, the main differential d
iagnosis is metastatic disease. There is no effective treatment for th
ese tumors, and although survival time is variable, the prognosis is g
enerally unfavorable.