MANAGEMENT OF FIBROUS HISTIOCYTOMA OF THE CORNEOSCLERAL LIMBUS - REPORT OF A CASE AND REVIEW OF THE LITERATURE

Background: Fibrous histiocytomas of the corneoscleral limbus are rare tumors. We present an additional case and review the treatment approa ches in the literature. So far, only light and electron microscopic st udies have been performed. We used immunohistochemical stains to furth er characterize the cellular composition. Methods: The excised lesion was routinely fixed and processed for light microscopy and immunohisto chemical studies. For comparison, three dermal fibrous histiocytomas w ere also examined and processed similarly. Results: The corneolimbal t umor was mainly composed of fibroblasts and histiocytes with a large a mount of interstitial collagen, arranged in a storiform pattern. Immun ohistochemical stains were positive for histiocytes, fibroblasts, and a marker for mesenchymal cells. The staining pattern of the dermal les ions was similar. Conclusion: Fibrous histiocytomas of the corneolimba l region are morphologically benign, slowly growing and infiltrative t umors. Complete resection, especially of the deep margin, is suggested . The immunohistochemical staining pattern is similar to that of derma l fibrous histiocytomas, which behave in a benign manner.