HIRSCHSPRUNGS-DISEASE AS A NEUROCHRISTOPATHY

Authors
MARTUCCIELLO G
Citation
G. Martucciello, HIRSCHSPRUNGS-DISEASE AS A NEUROCHRISTOPATHY, Pediatric surgery international, 12(1), 1996, pp. 2-10
Citations number
74
Categorie Soggetti
Surgery,Pediatrics
Journal title
Pediatric surgery international → ACNP
ISSN journal
01790358
Volume
12
Issue
1
Year of publication
1996
Pages
2 - 10
Database
ISI
SICI code
0179-0358(1996)12:1<2:HAAN>2.0.ZU;2-Z
Abstract
Recent molecular-genetic and histochemical studies of intestinal agang lionosis have confirmed the initial classification established by Bola nde, who considered Hirschsprng's disease (HD) a neurocristopathy. Thi s paper is a critical review of the results of molecular-genetic studi es carried out from 1992 to date. In particular, the author focuses on the possible clinical impact of the identification of RET as a causat ive gene for HD.