A CASE OF PHILADELPHIA-NEGATIVE, M-BCR REARRANGED EOSINOPHILIC LEUKEMIA WITH TRISOMY-8 LOCALIZED BY IN-SITU HYBRIDIZATION

Authors
CHAN LC KWONG YL LIE AKW CHING LM
Citation
Lc. Chan et al., A CASE OF PHILADELPHIA-NEGATIVE, M-BCR REARRANGED EOSINOPHILIC LEUKEMIA WITH TRISOMY-8 LOCALIZED BY IN-SITU HYBRIDIZATION, Leukemia, 8(1), 1994, pp. 195-198
Citations number
17
Categorie Soggetti
Hematology,Oncology
Journal title
Leukemia → ACNP
ISSN journal
08876924
Volume
8
Issue
1
Year of publication
1994
Pages
195 - 198
Database
ISI
SICI code
0887-6924(1994)8:1<195:ACOPMR>2.0.ZU;2-I
Abstract
A case of Ph-negative M-BCR rearranged eosinophilic leukaemia with clo nal cytogenetic abnormalities is presented. In addition to involvement of the short arm of chromosome 12 (12p12?13), the malignant nature of the eosinophils was confirmed by the demonstration of trisomy 8 by in situ hybridization.