HDL-APOLIPOPROTEIN-E LEVELS ARE LOWERED IN PATIENTS WITH ACUTE CEREBRAL INFARCTION

Authors
GIROUD M GRAS P BOUTRON MC GAMBERT P DUMAS R
Citation
M. Giroud et al., HDL-APOLIPOPROTEIN-E LEVELS ARE LOWERED IN PATIENTS WITH ACUTE CEREBRAL INFARCTION, Cerebrovascular diseases, 4(2), 1994, pp. 92-95
Citations number
18
Categorie Soggetti
Cardiac & Cardiovascular System",Neurosciences
Journal title
Cerebrovascular diseases → ACNP
ISSN journal
10159770
Volume
4
Issue
2
Year of publication
1994
Pages
92 - 95
Database
ISI
SICI code
1015-9770(1994)4:2<92:HLALIP>2.0.ZU;2-H
Abstract
Serum apolipoprotein E (ApoE) was determined in 85 patients(72 +/- 9 y ears; mean age +/- SD) with acute cerebral infarction and in 170 contr ols matched for age and sex. Total ApoE levels were normal but HDL-Apo E levels were significantly lower in the stroke patients (21.85 +/- 9. 31 vs. 38.25 +/- 14.17 mg/l; p < 0.001). Patients with concomitant car diac arrhythmia tended to have the same lower levels than those withou t cardiac arrhythmia. Lower HDL-ApoE levels seem to be an important ri sk factor for cerebral infarction.