AGONIST-INDUCED PHOSPHATIDYLINOSITIDE BREAKDOWN AND MITOGENESIS IN RETINAL CAPILLARY PERICYTES

Authors
LI WY TAO L YANOFF M
Citation
Wy. Li et al., AGONIST-INDUCED PHOSPHATIDYLINOSITIDE BREAKDOWN AND MITOGENESIS IN RETINAL CAPILLARY PERICYTES, Ophthalmic research, 26(1), 1994, pp. 36-40
Citations number
29
Categorie Soggetti
Ophthalmology
Journal title
Ophthalmic research → ACNP
ISSN journal
00303747
Volume
26
Issue
1
Year of publication
1994
Pages
36 - 40
Database
ISI
SICI code
0030-3747(1994)26:1<36:APBAMI>2.0.ZU;2-I
Abstract
We have examined the effects of a variety of vasoactive agents and gro wth factors on phosphatidylinositide turnover and DNA synthesis in cul tured retinal capillary pericytes. A complex correlation between phosp hatidylinositide turnover and DNA synthesis varied with different agon ists. The resulting data indicate that phosphatidylinositide turnover is not the sole signaling pathway, and there must be multiple signalin g pathways involved in pericyte mitogenesis.