PLATELET MONOAMINE-OXIDASE ACTIVITY IN NEUROLEPTIC-NAIVE SCHIZOPHRENIC-PATIENTS - LACK OF INFLUENCE OF CHRONIC PERPHENAZINE TREATMENT

Authors
SPIVAK B KOSOWER N ZIPSER Y SHREIBERSCHUL N APTER A TYANO S WEIZMAN A
Citation
B. Spivak et al., PLATELET MONOAMINE-OXIDASE ACTIVITY IN NEUROLEPTIC-NAIVE SCHIZOPHRENIC-PATIENTS - LACK OF INFLUENCE OF CHRONIC PERPHENAZINE TREATMENT, Clinical neuropharmacology, 17(1), 1994, pp. 83-88
Citations number
31
Categorie Soggetti
Pharmacology & Pharmacy",Neurosciences
Journal title
Clinical neuropharmacology → ACNP
ISSN journal
03625664
Volume
17
Issue
1
Year of publication
1994
Pages
83 - 88
Database
ISI
SICI code
0362-5664(1994)17:1<83:PMAINS>2.0.ZU;2-C
Abstract
We investigated the possible relationship between schizophrenia, neuro leptic treatment, and platelet monoamine oxidase (MAO) activity. Plate let MAO activity was similar in neuroleptic-naive schizophrenic patien ts and healthy controls and was not affected by chronic (1O-week) perp henazine treatment. A relationship between platelet MAO activity and c entral disturbances in schizophrenia remains uncertain.