Dc. Rule, EFFECTS OF DIETARY FATTY-ACID COMPOSITION ON GLYCEROPHOSPHATE ACYLTRANSFERASE ACTIVITY IN RAT ADIPOSE-TISSUE AND LIVER, International Journal of Biochemistry, 26(1), 1994, pp. 49-54
1. How source of dietary fat influences glycerophosphate acyltransfera
se (GPAT) activity in homogenates of adipose tissue and liver was dete
rmined using 5 rats per diet that contained 12% fat from either corn-
(CO), high-oleate-safltlower (HOSO), palm- or high-stearate-oils. 2. A
ctivity was greatest in adipose tissue homogenates of rats fed HOSO an
d CO whereas no treatment effects were observed in liver homogenates.
3. No differences in fat pad weights were observed; thus HOSO- and CO-
diets likely depressed other lipid synthetic rates. 4. Data indicate t
hat mono- and diunsaturated fatty acid diets supported greater adipose
tissue GPAT activity than did saturated fat diets when fed to rats.