EFFECTS OF DIETARY FATTY-ACID COMPOSITION ON GLYCEROPHOSPHATE ACYLTRANSFERASE ACTIVITY IN RAT ADIPOSE-TISSUE AND LIVER

1. How source of dietary fat influences glycerophosphate acyltransfera se (GPAT) activity in homogenates of adipose tissue and liver was dete rmined using 5 rats per diet that contained 12% fat from either corn- (CO), high-oleate-safltlower (HOSO), palm- or high-stearate-oils. 2. A ctivity was greatest in adipose tissue homogenates of rats fed HOSO an d CO whereas no treatment effects were observed in liver homogenates. 3. No differences in fat pad weights were observed; thus HOSO- and CO- diets likely depressed other lipid synthetic rates. 4. Data indicate t hat mono- and diunsaturated fatty acid diets supported greater adipose tissue GPAT activity than did saturated fat diets when fed to rats.