A 48 year old woman was admitted with eyelid and peripheral edema. Uri
nalysis revealed nephrotic-range proteinuria; other studies disclosed
selective IgA deficiency. Kidney biopsy was normal apart from slight e
xpansion oi the mesangial matrix; no tubulointerstitial or vascular ch
anges were observed; by immunofluorescence no deposits were seen. Edem
a and proteinuria resolved spontaneously in ten days. We make some com
ments about glomerulopathies and IgA deficiency.