GRANULOCYTE-COLONY-STIMULATING FACTOR AS A TREATMENT OF LEUKOPENIA INA RENAL-TRANSPLANT RECIPIENT

We report a 45 yeard-old man who received a renal transplantation 30 m onths ago under immunosuppressive therapy with cyclosporin A, azathiop rine and prednisone. Allopurinol was started because of hyperuricemia with gouty crisis, and a proportional decrease of azathioprine dose wa s not implemented. Two months later the patient developed pancytopenia secondary to medullary hypoplasia. We describe the rapid recovery of neotrophil blood count under treatment with granulycyte-colony-stimula ting factor. No infectious complication was detected throughout the fo llow-up.