We report the case of a 40 yr old previously healthy woman who died su
ddenly during her second pregnancy from unusual coronary artery anomal
ies. The left anterior descending coronary artery arose from the above
of the right sinus of Valsalva 1.1 cm above the ridge in the aorta an
d coursed behind the pulmonary valve before it dipped deeply into the
myocardium of the interventricular septum. The left circumflex coronar
y artery was hypoplastic. The right coronary artery arose also from ab
ove the right sinus of Valsalva 1.1 cm above the ridge in the aorta bu
t was otherwise normal. A fourth small coronary artery arose between t
he origins of the left anterior descending and right coronary artery a
nd supplied the outflow tract of the right ventricle. Mild fibrosis wa
s present in the interventricular septum. The rest of the autopsy exam
ination was unremarkable. Such combination of coronary artery anomalie
s causing sudden unexpected death in a pregnant woman have not previou
sly been reported.