Twenty patients diagnosed as having multiple sclerosis (MS) were exami
ned by MRI and 9 neuropsychological scales: MMSE, BCRS, RMB, SDMT, BNT
, VM, FAS, Benton and Hamilton. The number and distribution of the les
ions, and cerebral and corpus callosum atrophy were evaluated by MRI.
MR images were generated by a 0.5 Tesla instrument utilizing T1WI, PD
and T2WI imaging techniques. The results reveal (1) that patients with
MS are impaired in a broad range of cognitive functions but mainly me
mory is affected; (2) number of lesions in the corona radiata, insula
and hippocampus is correlated with cognitive impairment, and (3) enlar
gement of the IIIrd ventricle is an indicator of memory impairment in
MS patients.