CORRELATION OF DEMENTIA, NEUROPSYCHOLOGICAL AND MRI FINDINGS IN MULTIPLE-SCLEROSIS

Citation
M. Tsolaki et al., CORRELATION OF DEMENTIA, NEUROPSYCHOLOGICAL AND MRI FINDINGS IN MULTIPLE-SCLEROSIS, Dementia, 5(1), 1994, pp. 48-52
Citations number
30
Categorie Soggetti
Neurosciences,Psychiatry
Journal title
ISSN journal
10137424
Volume
5
Issue
1
Year of publication
1994
Pages
48 - 52
Database
ISI
SICI code
1013-7424(1994)5:1<48:CODNAM>2.0.ZU;2-J
Abstract
Twenty patients diagnosed as having multiple sclerosis (MS) were exami ned by MRI and 9 neuropsychological scales: MMSE, BCRS, RMB, SDMT, BNT , VM, FAS, Benton and Hamilton. The number and distribution of the les ions, and cerebral and corpus callosum atrophy were evaluated by MRI. MR images were generated by a 0.5 Tesla instrument utilizing T1WI, PD and T2WI imaging techniques. The results reveal (1) that patients with MS are impaired in a broad range of cognitive functions but mainly me mory is affected; (2) number of lesions in the corona radiata, insula and hippocampus is correlated with cognitive impairment, and (3) enlar gement of the IIIrd ventricle is an indicator of memory impairment in MS patients.