Jc. Wallach et al., URBAN OUTBREAK OF A BRUCELLA-MELITENSIS INFECTION IN AN ARGENTINE FAMILY - CLINICAL AND DIAGNOSTIC ASPECTS, FEMS immunology and medical microbiology, 8(1), 1994, pp. 49-56
An outbreak of Brucella melitensis in a family was studied. From the f
ourteen family members who ate unpasteurized goat cheese nine became i
ll. Patients included four females and five males of 8 to 75 years old
. In seven of the patients the diagnosis was confirmed by positive blo
od culture for B. melitensis biovar 1. All the patients were analyzed
by standard tube agglutination (STA) and standard tube agglutination w
ith 2-mercaptoethanol (STA-2ME) tests at the time of diagnosis. In six
of the patients, ELISA assays were used to assess the humoral immune
anti-protein and anti-lipopolysaccharide (LPS) responses. Anti-LPS IgG
antibodies were detected in all of the patients. Anti-proteins IgG an
tibodies were present at significant levels in all the studied patient
s including the STA-2ME negative ones.