LONG-TERM NEUROBEHAVIORAL OUTCOME IN PEDIATRIC BRAIN-TUMOR PATIENTS -REVIEW AND METHODOLOGICAL CRITIQUE

This paper provides an overview of pediatric brain tumors and reviews the literature on long-term neurobehavioral outcomes for these childre n. Progress in this area has been slow due to numerous methodological and practical complications. While some general conclusions can be dra wn, the development of comprehensive models awaits more research into the multiplicity of biological and nonbiological events, and their int eractions, potentially affecting outcome. Increased theoretical and me thodological sophistication will be needed to address this complex cla ssification of diseases. Barriers to research in this area are enumera ted as are suggestions for future efforts.