Microwave irradiation provides good fixation of human and animal tissu
es for light and electron microscopy. In this study, microwave irradia
tion was used for the fixation of cytoplasmic and nuclear matrix in tu
mor cells. The nuclear matrix appeals well preserved and exhibits a ne
twork formed by thick and thin filaments. Hence microwave fixation can
be used as a quick and effective method for the study of the morpholo
gy of nuclear matrix.